http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2124219-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a0f72c66096c79f62800a395826ee550 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 |
| filingDate | 1983-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9761d919eb0dbf6a0dcca818c37eb192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e153dad6e812f36639c1c06947a3cbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cfcaa7f1092e82476633c6774a680e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f0ee83c2195773aa684949ccc5574f0 |
| publicationDate | 1984-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2124219-A |
| titleOfInvention | Thienobenzothiepins |
| abstract | 4-(1-Methyl-4-piperidylidene)- 4,9-dihydrothieno(2,3-c)-2- benzothiepin of formula I <IMAGE> and its hydrogen (+) tartrate (a novel salt) are prepared by the reaction of thieno(2,3-c)-2-benzothiepin-4(9H)- one with 1-methyl-4- piperidylmagnesium chloride in tetrahydrofuran and subsequent acid- catalysed dehydration of the resulting 4- (1-methyl-4-piperidyl)-4,9- dihydrothieno(2,3-c)-2-benzothiepin- 4-ol after removal of the simultaneously formed 7-(1-methyl-4- piperidyl)thieno(2,3-c)-2-benzothiepin -4(9H)-one. Compound I and especially its hydrogen (+) tartrate possess high antihistamine, antiserotonin, antireserpine and anticataleptic activity and are expected to find use in the therapy of migraine. |
| priorityDate | 1982-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.