| abstract |
Disclosed are novel carbapenem derivatives characterized by a 2- substitutent of the formula <IMAGE> wherein A represents C2-C6 straight or branched chain alkylene group and R<10> and R<11> each independently represents optionally substituted aliphatic, cycloaliphatic, cycloaliphatic- aliphatic, aryl, heterocyclyl, heterocyclyl-aliphatic, heteroaryl or heteroaraliphatic, or R<10> and R<11> taken together with the S<(+)> to which they are attached represent an optionally substituted sulfur-containing heterocyclic ring. Such derivatives are useful as potent antibacterial agents. Also disclosed are processes for the preparation of such derivatives. |