abstract |
An improved immunoassay method for the estimation of human luteinising hormone (LH) present in a sample comprises, (a) binding LH present in the sample to both a labelled receptor and an unlabelled receptor to form a solid labelled complex, and (b) analysing for either labelled receptor bound in the solid labelled complex or residual unbound labelled receptor, wherein the labelled receptor is a labelled monoclonal antibody to LH. Such monoclonal antibodies to LH are included within the scope of the invention, and in a preferred embodiment a conformational monoclonal antibody is provided e.g., anti-human LH No. ESI. |