http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2109378-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D219-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D219-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-04 |
filingDate | 1982-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94f429d2b88482b4e66dd2c21bcd535a |
publicationDate | 1983-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-2109378-A |
titleOfInvention | Method of preparing 1-formyl congeners of indole-dihydroindole dimers |
abstract | 1-Formyl congeners of the equivalent indole-dihydroindole dimers which are prepared by contacting a solution in tetrahydrofuran (THF) of unseparated indole dihydroindole dimeric alkaloids obtained from Vinca rosea leaves by extraction, with an aqueous chromate-sulfuric acid solution at a temperature in the range of between -80 DEG C. and -50 DEG C. until substantially all 1- methyl congeners initially present are converted to 1-formyl congeners; optionally, formylating any 1- desformyl congeners present; and isolating the same one or more 1- formyl congeners. This process eliminates a number of steps and is highly efficient. |
priorityDate | 1981-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.