| abstract |
Testosterone and 1- dehydrotestosterone are produced from androst-4-ene-3,17-dione, androsta-1,4-diene-3,17-dione or steroids with C2-8 17-side chains (e.g. sitosterol, cholesterol, stigmasterol, campesterol) using mutant microorganisms of genera Arthrobacter, Bacillus, Brevibacterium, Corynebacterium, Microbacterium, Mycobacterium, Nocardia, Protaminobacter, Serratia or Streptomycos, especially the novel Mycobacterium sp. NRRL B-12472 (a mutant of NRRL B-3805). |