http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2103211-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7b463a881c360b9d0189d5c53792d18 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-22 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 |
filingDate | 1982-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ce76dad93168dd10ccca445483fd514 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5e3d257a76a3e4301a2a6024f2efae5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9810dc2fc42ab0a9c1108ff34f42a23 |
publicationDate | 1983-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-2103211-A |
titleOfInvention | Manufacture of semisynthetic cephalosporins |
abstract | Semisynthetic cephalosporins of the formula: <IMAGE> wherein R is a hydrogen atom or a Cl-(CH2)3-CO-, Ph-CH2-O-CO- or Cl3C-CH2-O-CO- group or other amino protecting group and R' is a hydrogen atom or a Cl3-C-CH2- or CH(C6H5)2- group or other carboxy protecting group, are made by reacting an N-protected alpha-phenylglycine of the formula: <IMAGE> with an N-chlorocarbonyl-sec.amide or lactam of the formula: <IMAGE> wherein X is a bis(mono-C1-C6-alkyl) group, a C1-C6-alkyl diradical, a C1-C4- alkyl diradical containing a hetero-atom selected from N, O and S or a <IMAGE> group, wherein Y is a C1-C6 group or a C0-C4 group containing a heteroatom selected from N, O and S and n is an integer from 0 to 3, and subjecting the resultant mixed anhydride to selective aminolysis with an ester of 7- aminodeacetoxy-cephalosporanic acid. The final products are antibacterial agents or intermediates for their synthesis. |
priorityDate | 1981-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.