http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2101586-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a157f5faa443ba5bb3367371f1e2a6c7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-44 |
| filingDate | 1982-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_007713a146030016b54604fbf2b05d7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0e2c8b0d222a0e8b597db782725efc8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3f124e20790082a9230cb9c1e71b3fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01814a96afe83802a90770f9281b8f2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db7064deb93ce5ebe2c6c61871f8146d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb9ad10eac8ee7e5d456428c53b70e99 |
| publicationDate | 1983-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2101586-A |
| titleOfInvention | beta -Lactam compounds and pharmaceutical compositions containing the same, and a process for the preparation thereof |
| abstract | Ceph-3-em-4-carboxylic acid and 2,2-dimethyl-penam-3-carboxylic acid derivatives of the general formula (I), wherein: R<6>R<7>N- or R<6>R<7>-NR<4>-, X is -C(CH3)2-, -CH2-C(CH3)= -CH2-C(CH2OAc)= or -CH2-C(CH2SHet)=, Het is a 5-7 membered heterocyclic group containing 1-4 nitrogen atom(s) and optionally one or more other hetero atom(s), optionally condensed with one or more phenyl group(s) and/or substituted with one or more alkyl, aralkyl, aryl, substituted aryl or substituted aralkyl group(s), R<1> is hydrogen atom, a C1-4 alkyl group or a phenyl group bearing optionally a halo, hydroxy, alkoxy or alkyl substituent, R<2> is hydrogen atom, a C1-4 alkyl group or a phenyl group bearing optionally a halo, hydroxy, alkoxy or alkyl substituent, R<3> and R<8> each stand for hydrogen atom, a C1-4 alkyl group or a phenyl group bearing optionally a halo, hydroxy, alkoxy or alkyl substituent, Q represents oxygen, sulfur or selenium atom, R<4> is hydrogen atom, a C1-4 alkyl group or a group -COOR<5>, R<5> being a C1-8 alkyl group, a benzyl group, a benzhydryl group or a phenyl group bearing optionally a halo, hydroxy, alkoxy or alkyl substituent, R<6> is a phenyl group bearing optionally one or more halo, C1-6 alkyl, nitro, alkoxycarbonyl, trifluoromethyl, dialkylamino, hydroxy, carboxylic acid or sulfonic acid substituent(s), a C1-8 alkyl group optionally bearing an alkoxycarbonyl, hydroxyl, dialkylamino or alkoxy substituent, a C3-8 cycloalkyl group, a C2-6 alkenyl group, a naphthyl group, a heteroaryl group, a 3-8 membered heterocyclyl group optionally condensed with one or more phenyl group(s) and/or bearing one or more substituent(s), or an adamantyl group, and R<7> is hydrogen, or R<6> and R<7> form, together with the adjacent nitrogen atom, a 4-8 membered, unsubstituted or substituted heterocyclic group optionally containing one or more additional nitrogen, oxygen or sulfur atom(s) and optionally condensed with one or more phenyl ring(s), Z is hydroxy group, n is zero or one, and t is zero, one or two, and their pharmacologically acceptable salts and biologically active esters possess strong antimicrobial and enzyme inhibiting, particularly antibacterial and beta -lactamase inhibiting effects. |
| priorityDate | 1981-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 147.