| abstract |
Metronidazole retinoate and mizonidazole retinoate are useful in the treatment of acne by topical application. Pharmaceutical compositions comprising retinoic acid or a lower alkyl ester thereof and an ester of metronidazole or mizonidazole with an acid of formula RCOOH, in which R is an aliphatic residue such that RCOOH is an aliphatic acid of 3 to 10 carbon atoms, are useful for the same purpose. |