http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2086884-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69c91bbf0395db010b4806f50d808c4e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 1981-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1982-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2086884-A |
| titleOfInvention | Cytostatic Compounds |
| abstract | A process for the preparation of compounds of general formula <IMAGE> wherein either R<4> represents a beta -hydroxy group and R<3> represents a alpha -ethyl group, or R<4> represents a hydrogen atom and R<3> represents a beta -ethyl group; R'' represents a straight chained alkyl group having from 1 to 10 carbon atoms, a branched chained alkyl group having from 3 to 10 carbon atoms and in which the carbon atom attached to the >Na-CH2O- group has a primary or secondary configuration, an alkenyl group having from 3 to 6 carbon atoms, an alkynyl group having from 3 to 6 carbon atoms, a cycloalkyl group having from 5 to 7 carbon atoms or an aralkyl group containing 1 to 3 carbon atoms in the alkyl moiety; R1 is methoxy; and R2 is acetyl and epimers thereof, which comprises reacting a compound of formula above in which R'' differs from the desired value with a large excess of an alcohol R''-OH in which the value of R'' is the one desired. The compounds of general formula (I), other than those wherein R<3> represents an alpha -ethyl group, R<4> represents a beta -hydroxyl group and R'' represents an ethyl group, are also claimed per se and are of use as cytostatic agents. |
| priorityDate | 1980-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.