http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2078724-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7b463a881c360b9d0189d5c53792d18 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-084 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 |
| filingDate | 1981-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1982-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2078724-A |
| titleOfInvention | Carboxylic Acid Amides |
| abstract | Carboxylic acid amides which are sensitive compounds, including the penicillins and cephalosporin, are made by reacting a carboxylic acid with an N-chlorocarbonyl-sec-amide to form a mixed anhydride of the formula: <IMAGE> wherein R is a C1-5 alkyl, cycloalkyl of up to C6, aryl, aralkyl with up to C5 in the alkyl moiety or heterocyclic and X is bis[mono-(C1-C6)alkyl], C1-6 alkylene, a C1-4 group with N, O or S as a heteroatom or <IMAGE> where Y is a C1-5 group or a C0-4 group with N, O or S as a heteroatom and n is 0-3, and subjecting the mixed anhydride to aminolysis with an amine of the formula: <IMAGE> wherein R' and R'' are each H, C1-5 alkyl, cycloalkyl of up to C6, aralkyl having up to C5 in the alkyl moiety or heterocyclic. The carboxylic acid amide products have the formula: <IMAGE> wherein R, R' and R'' are as defined above. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6927290-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6753431-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1160236-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1160236-A3 |
| priorityDate | 1980-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.