http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2061914-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14effe3850d2129f863b969dac4f1db8 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-28 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-28 |
filingDate | 1979-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1981-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-2061914-A |
titleOfInvention | Substituted anilines and their use as anti-atherosclerotic agents |
abstract | Novel compounds useful as hypolipidemic and atherosclerotic agents are represented by the structural formulae: <IMAGE> wherein R1 is a saturated or unsaturated hydrocarbon radical of 7-19 carbon atoms which may be branched or unbranched and which may contain one or more radicals selected from the group consisting of saturated or unsaturated cycloalkyl, substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl; R2 is selected from the group consisting of hydrogen or a group convertible in vivo thereinto such as methyl, carboxymethyl, acetyl, succinyl, 1-(sodium-sulfo) loweralkyl, 1- (sodiumsulfo)polyhydroxyalkyl, and 3- aryl-1,3-bis-(sodiumsulfo)alkyl; and a) J is <IMAGE> Z is selected from the group consisting of hydrogen, loweralkyl, hydroxy, loweralkoxy, loweralkoxyalkoxy, di-loweralkylaminoalkoxy. (mono- or polyhydroxy) loweralkoxy, allyloxy, 2,3-epoxypropoxy, substituted or unsubstituted benzyloxy, substituted or unsubstituted phenoxy and 3- pyridyloxy, pyridylmethoxy, (mono- or polycarboxy) loweralkoxy, (mono- or polycarboxy) hydroxyloweralkoxy, tetrahydropyranyloxy, (mono- or polyhydroxy)alkylamino, allylamino, propargylamino, 2-sulfoethylamino, (mono- or polycarboxy) loweralkylamino, (mono- or polycarboalkoxy)loweralkylamino, loweralkanoylamino, (substituted or unsubstituted) aroylamino, loweralkanesulfonylamino, (substituted or unsubstituted) arenesulfonylamino, loweralkanoylhydrazino, hydroxylamino, polymethyleneimino, (4- carboethoxy- or 4-carboxy) thiazolidino, loweralkyl bearing one or more carboxy, carboalkoxy, carbamoyl, acyl, sulfinyl, or sulfonyl groups, or b) J is carboxyloweralkyl, carboxyloweralkenyl, carboxyloweralkynyl, carboalkoxyloweralkyl, carboalkoxyloweralkenyl, carboalkoxyloweralkynyl; and the pharmaceutically acceptable non- toxic acid-addition and cationic salts thereof. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010510242-A |
priorityDate | 1979-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 499.