http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2054572-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-38 |
| filingDate | 1980-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1981-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2054572-A |
| titleOfInvention | Thiophene carboxamides |
| abstract | Thiophene carboxamides are described of general formula I: <IMAGE> in which the amide function is in the 2- or 3-position on the thiophene ring, R1 to R5 inclusive are hydrogen atoms or lower alkyl groups, X is -CH2-, -O- or -NR6- where R6 is hydrogen or a lower alkyl group, n is a number from 0 to 3 with the proviso that when n is zero X cannot represent -O- or -NR6- and Ar is an optionally substituted phenyl group and their physiologically acceptable salts. The compounds have been found to lower blood pressure in animals and to exhibit a blocking action at beta -adrenoreceptors and their use is indicated for the treatment of cardiovascular and disorders such as hypertension and angina. Some of the compounds also exhibit a blocking action on alpha -adrenoreceptors and their use is indicated for the treatment of hypertension. The compounds may be formulated in conventional manner together with physiologically acceptable carriers or excipients. |
| priorityDate | 1979-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.