http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2051047-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a157f5faa443ba5bb3367371f1e2a6c7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 |
| filingDate | 1980-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1981-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2051047-A |
| titleOfInvention | Anti-Anginal 3-Substituted Hexahydro-Pyrimido[1,2-a] Azepines |
| abstract | A process for the preparation of pyrimido[1,2-a]azepines of the general formulae I <IMAGE> and mixtures and pharmaceutically suitable salts wherein R is hydrogen or lower alkyl, R<1> is lower alkyl, phenyl, carboxyl, lower alkoxycarbonyl, nitrile, carbamoyl or carbohydrazido, R<2> is hydrogen or lower alkyl comprises reacting a compound of the formula III <IMAGE> wherein R is defined as above with a compound of the formula IV <IMAGE> wherein R<2> is as defined above, R<3> lower alkyl, phenyl, lower alkoxycarbonyl, nitrile, R<4> is hydrogen or lower alkyl R<5> is lower alkyl and optionally transforming the initial product(s). Most of the compounds of general formulae I and II are novel. The compounds are of interest in the treatment of angina. |
| priorityDate | 1979-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 118.