http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2036015-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5712b4838bdb16ebbc41121239e165b9 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-568 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-09 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-568 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-09 |
filingDate | 1979-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1980-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-2036015-A |
titleOfInvention | Process for preparing penem derivatives |
abstract | A process for the preparation of the compounds of the formula (II): <IMAGE> and salts and cleavable esters thereof wherein R1 is a hydrocarbon group of up to 12 carbon atoms and which optionally also contain up to 4 heteratoms selected from oxygen, nitrogen, sulphur or chlorine and bromine which process comprises the reaction of a cleavable ester of a compound of the formula (III): <IMAGE> with one equivalent of a strong base of low nucleophilicity and thereafter with a compound of the formula (IV) or (V): <IMAGE> wherein R<1>1 is a group R1 in which any amino substituent is protected and R<2> is an alkyl group of 1-4 carbon atoms optionally substituted by a phenyl group or is a phenyl group optionally substituted by an alkyl group off carbon atoms and thereafter if desired cleaving the ester moiety to yield the acid of the formula (II) or a salt thereof and removing the protecting group from any protected amino group present in R<1>1; is described. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9403168-A1 |
priorityDate | 1978-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 127.