http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2033223-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b0369d9e0ba708437730de73cb5c0005 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-64 |
| filingDate | 1979-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1980-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2033223-A |
| titleOfInvention | Antigen from Streptococcus Mutans for Protection Against Dental Caries |
| abstract | An antigenic protein, termed antigen A, obtained from cultures of Streptococcus mutans, especially genetic group I (serotypes c, e and f) is separated from other antigenic proteins, notably those which cross- react with heart tissue, to give an antigenic preparation which may be used as a vaccine or to raise antibodies for use in protecting against dental caries. Antigen A has a molecular weight of about 29,000, and an isoelectric point of 4.1 to 4.5. Its amino-acid analysis is also given. The antigen may be obtained from the culture filtrate and/or cell extract and may be readily purified from these sources by, for example fractional ammonium sulphate precipitation and/or affinity chromatography on immobilised antibody. The antigen may be formulated into a vaccine with an injectable carrier and optionally an adjuvant (e.g. aluminium hydroxide), or alternatively may be injected into animals to raise antibodies which may be formulated with a pharmaceutical carrier into preparations for administration by injection or by swallowing, or for topical oral application (e.g. toothpastes and mouthwashes) for protection against dental caries. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0080806-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2176400-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1023903-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8204396-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2176400-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0140498-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4521513-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0068660-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4659561-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-3619904-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2143829-A |
| priorityDate | 1978-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.