http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-201212853-D0
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca48c26073291564d19a8da2910e42b7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-952 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0808 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B11-24 |
| filingDate | 2012-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-201212853-D0 |
| titleOfInvention | Compound |
| abstract | Rhodamine compounds and their uses for detecting coagulase-producing bacterial strains Rhodamine bis(tripeptide) compounds of formula I: wherein X is C(O) or S(O)1-2; Y is O, S, NH or CH2; R1a and R1b are H or C1-6alkyl, where the alkyl group may be substituted with halo; R2a and R2b are H, C(O)Ra, C(O)ORb, L-aryl or a G group; R3a, R3b, R4a and R4b are H, NO2, OH, C(O)Rc or optionally halo-substituted C1-6alkyl; m is 0-3; n is 0-4; each R5 is halo or other substituents; or two or more R5 groups may be joined together with the carbon atoms to which they are attached a 5- or 6-membered aryl or cycloalkyl group; each R6 is NHRf, NRgRh, C(O)Rh, ORi, or optionally halo substituted aryl or C1-6alkyl; Ra-Ri are optionally halo-substituted C1-6alkyl; L is a direct bond or CH2; G is any amino acid which may be further substituted; may be useful for the detection of coagulase-producing bacterial strains, particularly Staphylococcus aureus. The preferred compound is rhodamine coupled to the N-Boc protected tripeptide Val-Pro-Arg. The compounds are useful in detecting methicillin resistant Staphylococcus aureus (MRSA) and MSSA. |
| priorityDate | 2012-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.