http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2009180-A

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filingDate 1978-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1979-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-2009180-A
titleOfInvention 25-Alkyl Cholesterol Derivatives
abstract Compounds of formula (A): <IMAGE> wherein R2 is an alkyl group having from 1 to 4 carbon atoms, R is a hydrogen atom, an alkanoyl group having from 2 to 7 carbon atoms, or a radical of the formula: <IMAGE> in which n is a positive integer less than 4, Y is a methylene or carbonyl group, provided that when Y is a carbonyl group, R1 is a hydrogen atom, and when Y is a methylene group, R1 is the group OX in which X is a hydrogen atom, an alkanoyl group having from 2 to 7 carbon atoms, or a radical of the formula: <IMAGE> in which n is a positive integer less than 4, and the wavy line represents R or S stereochemistry, processes for their preparation, pharmaceutical and veterinary formulations containing them, and their uses as inhibitors of the activity of HMGCoA reductase and as antiprotozoal agents.
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Total number of triples: 25.