abstract |
Prostane derivatives have the following formula <IMAGE> in which the substituents are defined in Claim 1. The novel compounds are prepared by appropriately esterifying corresponding prostan-1-ols in which free OH groups, with the exception of the 1-OH group, have optional intermediate protection. A further process is based on the reaction of the prostan-1-ols with isocyanates or with carbamoyl chlorides. The novel prostane derivatives are used in medicaments. They can be used for inducing an abortion, for cycle control, for induction of labour or for the treatment of hypertension. |