http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1536425-A

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filingDate 1976-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1978-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1536425-A
titleOfInvention Blood treatment
abstract 1536425 Blood purification NATIONAL RESEARCH DEVELOPMENT CORP 30 Jan 1976 [6 Fob 1975] 5101/75 Heading C3H A biocompatible material for removing from blood an undesirable substance capable of being bound to a plasma protein comprises a support material rendered biocompatible by a coating of a biocompatible substance, which support material is a manoreticular polymer having an affinity for one or more of the substances unconjugated bilirubin, cholic acid, chenodeoxycholic acid and lithocholic acid. The biocompatible substance is preferably a plasma constituent, e.g. HSA. The affinity of the support material is preferably such that the concentration of one of the substances unconjugated bilirubin, cholic acid, chenodeoxycholic acid and lithocholic acid on the uncoated support material at equilibrium with a 15 mg. per cent solution of the substance in normal human plasma at pH 7.4 is at least 10% of the concentration of the substance on the coated material under identical conditions. The concentration of one of said substances on the uncoated support material may be at least 20% of the concentration of the substance on the coated material under said conditions. The biocompatible material may have a water content which is no greater than 80% by weight, and it is preferably particulate. A biocompatible material according to any preceding claim in which the support material is a synthetic resin, e.g. methacrylic or acrylic polymer or copolymer.
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priorityDate 1976-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 27.