| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97a285d8ecd0184a7e5d89a1e4e07997 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-234
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-236
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-234
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate |
1975-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
1978-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
GB-1535215-A |
| titleOfInvention |
Kanamycin derivatives |
| abstract |
Semisynthetic derivatives of kanamycin A and B of the formula IV in which R3 and R have the meaning stated in Claim 1 are prepared. The process starts from corresponding compounds with R = hydrogen and comprises acylation with an acylating agent of the formula VII in which W and M have the meaning stated in Claim 1, and subsequent elimination of the amino protective group W. A preferred acylating agent of the formula VIIa is obtained in situ by mixing the appropriate N-protected carboxylic acid with equimolar amounts of N-hydroxy-5-norbornene-2,3-dicarboximide and dicyclohexylcarbodiimide as dehydrating agent. The said compounds have antibacterial activity and can therefore be used in medicines or as additives to animal feedstuffs. <IMAGE> |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8524689-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8653042-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8822424-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11117915-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8658606-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9688711-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9266919-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE47741-E
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8492354-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8383596-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8524675-B2 |
| priorityDate |
1974-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |