http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1528011-A

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_70ec63d39d6704bacc5c7068c93ded43
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-32
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-32
filingDate 1975-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1978-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1528011-A
titleOfInvention Continuous culture of micro-organisms
abstract 1528011 Continuous cultivation of bacteria &c on methanol &c SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ BV 9 Feb 1976 [11 Feb 1975] 5747/75 Heading C6F In a process for the production of microorganisms involving continuously cultivating one or more hydrocarbon or oxygenated hydrocarbon utilizing micro-organisms under aerobic conditions in a liquid growth medium comprising assimilable sources of nitrogen and essential mineral salts in the presence of a hydrocarbon or oxygenated hydrocarbon, withdrawing from the growing culture, liquid growth medium containing micron organisms, separating micro-organisms from the withdrawn liquid growth medium and recycling at least part of the withdrawn liquid growth medium to the growing culture, the withdrawn liquid growth medium is chilled to a temperature in the range of -5‹ to +20‹C prior to, or during, the separation of the micro-organisms. It is stated that any buildup of growth-inhibiting material during the separation stage is avoided and contamination of the separation and recycle lines by undesirable anaerobic micro-organisms is discouraged as a result of the chilling. The hydrocarbon or oxygenated hydrocarbon may for example be natural gas, methane or methanol. The Examples relate to the continuous cultivation of a mixed culture of microorganisms comprising a methanol-utilizing bacterium and four non-methanol utilizing bacteria in methanolic culture medium, with recycle of the culture medium and recovery of the micro-organisms produced. The cultivation temperature was 40‹ or 42‹C and the chilling temperature 0‹C. Growth inhibition was encountered when recycling took place without the chilling according to the invention.
priorityDate 1975-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 18.