http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1525166-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac3231be0616b804fa9cbe7b79f46577 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-088 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-088 |
| filingDate | 1976-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1978-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1525166-A |
| titleOfInvention | Piperazine derivatives |
| abstract | 1525166 Piperazine derivatives PARCOR 21 Oct 1976 [22 Oct 1975 30 July 1976] 43748/76 Heading C2C Novel compounds I:- in which R 1 is H, halogen, CF 3 , C 1-6 alkyl or C 1-6 alkoxy, R 2 is (a) C 5-8 cycloalkyl (optionally substituted by one or more alkyl groups), or (b) phenoxyalkyl, or (c) phenylalkyl, furylalkyl or thienylalkyl optionally substituted in the ring by 1 to 3 of halogen, C 1-6 alkyl, or C 1-6 alkoxy, or (c) the group -C(R 3 R 4 )-C#CH, in which each of R 3 and R 4 is H or C 1-6 alkyl or R 3 and R 4 , together with the adjacent C atom, represent a saturated 5-7 membered carbocyclic ring, and n is 2 or 3, and acid addition and quaternary ammonium salts thereof, are prepared by reacting a compound II: in which X is halogen, with a compound R 2 OH, followed, if desired, by converting a free base into an appropriate salt. Pharmaceutical compositions having analgesic, sedative and tranquillizing activity, for oral, parenteral or rectal administration, comprise one of the above novel compounds together with a pharmaceutical carrier. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7390812-B2 |
| priorityDate | 1975-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID456171974 |
Total number of triples: 12.