http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1523598-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7fa68ae66fed2f54717da32e57f7735f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0825 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-097 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C403-14 |
| filingDate | 1975-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1978-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1523598-A |
| titleOfInvention | Tripeptides |
| abstract | 1523598 Tripeptides RECKITT & COLMAN PRODUCTS Ltd 19 Feb 1976 [8 March 1975] 10144/75 Heading C3H [Also in Division C2] Peptides of formula wherein R is hydrogen or C1-C3 alkyl; R<1> is C1-C3 alkyl; R<2> is hydrogen or C1-C3 alkyl; R<3> is hydrogen, C1-C6 alkyl or C3-C6 cycloalkyl; R<4> is hydrogen or C1-C6 alkyl In the Examples, compounds prepared are: L - pyroglutamyl- L - histidyl - trans - 3 - methyl- L-prolineamide; L - pyroglutamyl - L - histidyl - trans - 3 - ethyl- DL-prolineamide; L - pyroglutamyl - L - histidyl - 3,3 - dimethyl- DL-prolineamide; L - pyroglutamyl - N<#> - methyl - L - histidyltrans-3-methyl-L-prolineamide; L - pyroglutamyl - L - histidyl - trans - 3 - methyl- L-prolinecyclohexylamide; L - pyroglutamyl - L - histidyl - trans - 3 - methyl- L-proline-n-hexylamide. Peptide intermediates isolated are: Benzyloxycarbonyl - L - pyroglutamyl - N<#>- methyl - L - histidine. Pharmaceutical compositions comprise the tripeptides in admixture with a pharmaceuticallyacceptable carrier or diluent, preferably, when used for oral administration, in unit dosage form wherein the dose is 1 to 100 mg. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5212158-A |
| priorityDate | 1975-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.