| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2de3beee83d9c19278da409b72c777a8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-12 |
| filingDate |
1975-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
1978-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
GB-1520522-A |
| titleOfInvention |
16-methyleneprostaglandins |
| abstract |
1520522 Silylated 16-methyleneprostaglandins; cyclodextrin clathrates ONO PHARMACEUTICAL CO Ltd 7 May 1976 [16 June 1975] 25591/75 Addition to 1449882 Headings C3S and C3U [Also in Division C2] The invention comprises cyclodextrin clathrates of 1b methyleneprostaglandins of the Formula IV wherein A is a grouping of the Formula II or III; R<1> is H or C1-6 alkyl, R<2> is H or C1-12 alkyl and X is trans-vinylene or ethylene, and their preparation by known methods. The invention also comprises trimethylsilyl derivatives of the Formula VII wherein R<5> is C1-12 alkyl; TMS is trimethylsilyl and R<1> and X are as defined above; and then preparation by known methods. Methyl 9alpha - hydroxy - 16 - methylene - 11alpha, 15alphabis(trimetlylsilyloxy) - prost - trans - 13 - enoate is obtained by silylating 16-methyleneprostaglandin F1alpha methyl ester. |
| priorityDate |
1975-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |