http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1508517-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44c713790ce00813da2e6c6d57a29456 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-0015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-0085 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
| filingDate | 1976-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1978-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1508517-A |
| titleOfInvention | Method for preparing 17alpha-ester-21-halo pregnanes |
| abstract | 1508517 Preparation of 17-acyloxy-21-halo- 20-keto-pregnanes TAISHO PHARMACEUTICAL CO Ltd 5 March 1976 [31 March 1975 1 May 1975] 08947/76 Heading C2U A 17α - acyloxy - 21 - halo - 20 - keto - pregnane compound wherein the acyl group is C 2-10 alkanoyl, (C 4-6 cycloalkyl)carbonyl, optionally substituted benzoyl or aralkanoyl is prepared by reacting an appropriate C 1-5 alkyl ortho ester of a 17α,21-dihydroxy-20-ketopregnane compound with a silyl halide, a carboxylic acid halide, a phosphorous oxyhalide, a sulphonyl halide, an N-halo-amide or imide or a phosphorous pentahalide in dimethylformamide, N - methylpyrrolidone, hexamethyl phosphoric acid triamide or dimethylsulphoxide or a mixture of one of these with an organic non-polar solvent. The ortho-ester starting materials are prepared from the free 17α,21-diols and RC(OR 1 ) 3 wherein R 1 is C 1-5 alkyl and R is a group which as RCO forms the above defined acyl group. |
| priorityDate | 1975-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.