http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1508314-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5712b4838bdb16ebbc41121239e165b9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-57 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 |
| filingDate | 1974-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1978-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1508314-A |
| titleOfInvention | 7-alpha-methoxy-7-beta-(substituted-acetamido)-cephalosporins and methods for their preparation |
| abstract | 1508314 7 - α - Methoxy - 7 - # - (substituted acetamido) - cephalosporins BEECHAM GROUP Ltd 21 Oct 1975 [10 Dec 1974] 53463/74 Heading C2C Novel compounds II or a salt or ester thereof in which Y is O or S, R<SP>1</SP> is an organic radical having up to 20 C atoms, R<SP>2</SP> is C 1-3 alkyl or benzyl or R<SP>1</SP> and R<SP>2</SP> together with the C and N atoms to which they are attached form a 5 to 7 membered ring, R<SP>3</SP> is phenyl (optionally substituted by one or more groups selected from OH, halogen, NO 2 , C 1-3 alkoxy and NH 2 ), thienyl, C 3-7 cycloalkyl, cyclohexadienyl, or C 1-4 alkyl and R<SP>5</SP> is an organic radical containing at least one O, N or S atom and which is linked to the 3-methylene moiety by one of these O, N or S atoms, are prepared by methods known per se. Sodium 7 - # - [D - α - (3 - cinnamoyl - 3- methylureido) - phenylacetamido] - 7 - α - methoxycephalosporanate and sodium 3 - carbamoyloxymethyl - 7 - α - methoxy - 7 - # - [D - α - (3 - (2- methyl - 2 - butenoyl) - 3 - methylureido) - phenylacetamido] - 3 - cephem - 4 - carboxylate are prepared. 3 - Hydroxymethyl - 7 - α - methoxy - 7 - # - [D- α - (3 - (2 - methyl - but - 2 - enoyl) - 3 - methylureido) - phenylacetamido - 3 - cephem - 4 - carboxylic acid is prepared by hydrolysis of the corresponding 3-acetoxymethyl derivative using citrus acetylesterase. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4301161-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4298605-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4341776-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4328224-A |
| priorityDate | 1974-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.