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filingDate 1976-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1978-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1507118-A
titleOfInvention Antibiotic derivatives of 3',4'-dideoxykanamycin b and the preparation thereof
abstract 1507118 N-sulphomethyl-3<SP>1</SP>,4<SP>1</SP>-dideoxy-kanamycin B derivatives ZAIDAN HOJIN BISEIBATSU KAGAKU KENKYU KAI 15 Sept 1976 [25 Sept 1975] 38256/76 Heading C2C Novel N - sulphomethyl - 3<SP>1</SP>,4<SP>1</SP> - dideoxykanamycin B derivatives of the general formula wherein R is hydrogen or optionally substituted alkyl or phenyl, M is hydrogen or an alkali metal and n is 1-5, are prepared by reacting 3<SP>1</SP>,4<SP>1</SP> - dideoxy - kanamycin B or an acid addition salt thereof with sulphurous acid or an alkali metal hydrogen sulphite and an aldehyde of the general formula RCHO. Pharmaceutical compositions having antibacterial activity comprise, as active ingredient, a N - sulphomethyl - 3<SP>1</SP>,4<SP>1</SP> - dideoxy - kanamycin B derivative of the first general formula above, together with a pharmaceutically acceptable carrier therefor.
priorityDate 1975-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 27.