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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-08
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filingDate 1976-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1978-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1501074-A
titleOfInvention Derivatives of salicylic acid suitable for use in therapeutics
abstract 1501074 Salicylic acid derivatives SOC D'ETUDES ET APPLICATIONS CHIMIQUES (SEAC) 24 March 1976 [24 March 1975] 11908/76 Heading C2C Novel compounds of formula in which X has one of the formulĀµ -OR 1 and -NHR 2 in which R 1 is a hydrogen atom or a straight or branched chain aliphatic hydrocarbon group having 1 to 7 carbon atoms, an aliphatic hydrocarbon group having 1 to 7 carbon atoms linked to a tertiary nitrogen atom or linked to a saturated heterocycle having 5 or 6 ring atoms including a tertiary nitrogen atom and which may also include an oxygen atom, and R 2 is a hydrogen atom or a straight or branched chain aliphatic hydrocarbon group having 1 to 6 carbon atoms, an aliphatic hydrocarbon group having 1 to 6 carbon atoms linked to a tertiary nitrogen atom or linked to a saturated heterocycle having 5 or 6 ring atoms including a tertiary nitrogen atom and which may also include an additional nitrogen atom or an oxygen atom, said tertiary nitrogen atom being separated from the amide nitrogen by at least two carbon atoms, together with (a) salts of said acid with mineral and organic bases and (b) salts of said esters and amides containing a tertiary nitrogen atom with mineral and organic acids, are prepared by esterifying salicylic acid with 2-(4-chlorophenoxy)isobutyric acid, or a functional derivative thereof, followed, if required, by esterifying or amidating the carboxylic functional of the resulting derivative. Pharmaceutical compositions for treating inflammatory conditions and complaints due to blood clotting comprise a compound of the invention together with a pharmaceutical carrier.
priorityDate 1975-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 26.