http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1496980-A

Outgoing Links

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filingDate 1975-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1978-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1496980-A
titleOfInvention Process for removing formyl groups from n-formyl protected esters
abstract 1496980 Process for the removal of formyl groups from N-formylated amino acid and peptide esters AJINOMOTO CO Inc 25 Nov 1975 [5 Dec 1974] 48458/75 Heading C2C [Also in Division C3] The invention comprises a process for removing a formyl group from the nitrogen atom of an N-formylamino acid ester which comprises reacting said ester with an at least equimolar amount of hydroxylamine in an inert liquid medium until the corresponding amino acid ester is formed, at least 70% of the hydroxylamine being present in the medium as a salt with a strong acid having a dissociation constant, or in the case of a polybasic acid, a first dissociation constant of not less than 1À0 Î 10<SP>-1</SP> at 25‹ C. the remainder, if any, being present in the medium as the free base or as the salt of a weak acid having a dissociation constant, or in the case of a polybasic acid, a first dissociation constant, less than 1À0 Î 10<SP>-1</SP> at 25‹ C. Specific compounds treated by the method of the invention are N-formyl-L-aspartic acid, α methyl ester and N-formyl-L-phenylalanine methyl ester.
priorityDate 1974-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 26.