http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1489104-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acae202b6a15394281949545e70d2f6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-224 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-234 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-234 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-224 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-06 |
filingDate | 1975-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1977-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1489104-A |
titleOfInvention | 4-o-alpha,d-glucopyranosyl-6-o-alpha,d-xylo-hexopyranosyl-2-deoxystreptamine a process for its preparation and compositions incorporating it |
abstract | 1489104 A 4-O-α,D-glucopyranosyl-6-O- α,D - xylohexopyranosyl - 2 - deoxystreptamine ROUSSEL-UCLAF 12 March 1975 [12 March 1974] 10271/75 Heading C2C Novel compound Iα and acid addition salts thereof is prepared by alkaline hydrolysis of a compound XIIα or a mixture thereof with the #-anomer and, if necessary, separating the compound Iα from its #-anomer. Compound XIIα and its #-anomer are prepared by Konigs-Knorr condensation of a compound X with a compound VII and hydrogenolysis of the benzyl group. Compound X is prepared by acid hydrolysis of 3<SP>1</SP>,4<SP>1</SP> - di - O - acetyl - 5,6 - O - cyclohexylidenetetra - N - methoxycarbonyl - neamine which is prepared by acetylation of 5,6-O-cyolohexylidene-tetra-N-methoxycarbonyl-neamine. Compound VII is prepared from compound II by demethylation of the NH-CH 3 group followed by reaction with Cl-COOEt to give NH-COOC 2 H 5 benzylation of the 2-OH group, substitution of 1-OC 2 H 5 by 1-OCOCH, and chlorination to give 1-Cl. Compound (Iα) has antibiotic activity and forms with a suitable vehicle a pharmaceutical composition which may be administered orally, parenterally, rectally or topically. |
priorityDate | 1974-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458394834 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID455824109 |
Total number of triples: 18.