http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1488617-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4f9105c55e374d7b68084726c14a253 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-74 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-74 |
| filingDate | 1975-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1977-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1488617-A |
| titleOfInvention | Pharmaceutical composition |
| abstract | 1488617 Pharmaceutical compositions BIOSCAL GmbH 21 March 1975 [23 March 1974] 11989/75 Heading A5B '[Also in Division C6] An orally administrable pharmaceutical composition for the alleviation of uremic symptoms in patients with kidney disease consists essentially of a cell mass of non- pathogenic soil bacteria that are active in the gastrointestinal tract and capable of degrading urea, creatine creatinine and/or uric acid. The cell mass is obtained by cultivating a selected species on a culture medium (disclosed) containing as substrate the respective substance intended to be degraded, recovering and freeze-drying the biomass produced, and forming it into orally administrable unit dosage forms e.g. capsules, using conventional procedures. The urea-degrading soil bacterium may be of the genus Serratia, and the creatinine-degrading bacterium of a Rhizobium, Agrobacterium or non-fluorescent Pseudomonas species, but other species of bacteria (and other micro-organisms) suitable for degrading creatinine or uric acid are mentioned in the context. Some strains of soil bacteria under test were found to degrade all twelve of the following compounds viz urea, guanidine, ornithine, arginine, creatine, creatinine, uric acid, glutamic acid, histamine, xanthine, allantoin and agmatine. |
| priorityDate | 1974-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.