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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D335-02
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D335-02
filingDate 1974-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1977-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1479916-A
titleOfInvention Benzothiadiazine derivatives
abstract 1479916 7 - Sulphamoyl - 3,4 - dihydro- 1,2,4 - benzothiadiazine - 1,1 - dioxides LABORATOIRE L LAFON 26 Nov 1975 [27 Nov 1974] 51273/74 Heading C2C Novel 7-sulphamoyl-3,4-dihydro-1,2,4- benzothiadiazines of the general FormulĀµ I wherein X is a halogen atom or CF 3 group, are prepared by reacting in an alcohol and in the presence of hydrochloric acid a tetrahydropyran of the general formula wherein A is -CHO, with a 2,4-disulphamoylaniline of the general formula 3 - Formyl - 5,6 - dihydro - (2H) - thiopyran (characterized as the semicarbazone or dinitrophenylhydrazone) is prepared by reacting 3- chloropropionaldehyde diethyl acetal with hydrated sodium sulphide in ethanol, followed by H 2 SO 4 , and may be reduced catalytically to give 3-formyltetrahydrothiopyran (characterized in the same way). Pharmaceutical compositions having diuretic activity comprise, as active ingredient, at least one compound of the Formula I, together with a physiologically acceptable excipient.
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priorityDate 1974-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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