http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1478261-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f6e33603375c486b0ab3505830af9e8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08K5-3435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-74 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08K5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08K5-3412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08K5-3435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L101-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-113 |
| filingDate | 1975-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1977-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1478261-A |
| titleOfInvention | Derivatives of 4-oxopiperidines |
| abstract | 1478261 Derivatives of 4-oxopiperidines CIBA-GEIGY AG and SANKYO CO Ltd 14 May 1976 [28 May 1975] 23228/75 Heading C2C The invention comprises compounds of the Formula I or mixtures of isomers thereof or acid addition salts thereof, wherein n is 1 or 2, R<SP>1</SP> is alkyl having 2-6 C-atoms, R<SP>2</SP> is alkyl having 1-6 C-atoms, R<SP>3</SP> is alkyl having 1-9 C-atoms, phenyl, benzyl or phenethyl, R<SP>4</SP> is alkyl having 1-6 C-atoms, or R<SP>3</SP> and R<SP>4</SP> together with the C-atom to which they are attached represent a cyclopentyl or cyclohexyl group, R<SP>5</SP> is alkyl having 1-5 C-atoms, alkenyl or alkinyl having 3-4 C-atoms or aralkyl having 7-8 C- atoms, R<SP>6</SP> is hydrogen, alkyl having 1-5 C- atoms, alkenyl or alkinyl having 3-4 C-atoms, aralkyl having 7-8 C-atoms and R<SP>5</SP> and EG are interchangeable, X is hydrogen, the oxyl radical, alkyl having 1-8 C-atoms, alkenyl having 3-6 C-atoms, alkinyl having 3-6 C- atoms, alkoxyalkyl having 2-21 C-atoms, aralkyl having 7-8 C-atoms, the 2,3-epoxypropyl group, an aliphatic acyl group having 1-12 C-atoms, or one of the groups wherein R<SP>7</SP> is alkyl having 1-12 C-atoms, alkenyl having 3-6 C-atoms, phenyl, aralkyl having 7-8 C-atoms or cyclohexyl, R<SP>8</SP> is H, CH 3 or phenyl, R<SP>9</SP> is H or an aliphatic, aromatic araliphatic or alicyclic acyl group having up to 18 C-atoms, which may optionally be substituted in its aryl moiety with chlorine, alkyl having 1-4 C-atoms, alkoxy having 1-8 C- atoms and/or hydroxy, R<SP>10</SP> is alkyl having 1-12 C-atoms, benzyl, phenyl or cyclohexyl and if n is 1, Y is one of the groups wherein R<SP>11</SP> is hydrogen, methyl or -CH 2 OR<SP>14</SP>, R<SP>12</SP> is hydrogen, methyl or ethyl, R<SP>13</SP> is hydrogen, methyl or ethyl, R<SP>14</SP> is hydrogen or a monovalent acyl residue derived from an aliphatic, cycloaliphatic, aromatic or araliphatic monocarboxylic acid having up to 18 C-atoms, which may be substituted in its aryl moiety with halogen, hydroxy and/or C 1-4 alkyl groups, or B<SP>14</SP> is alkyl having 1-4 C-atoms, alkenyl having 3 or 4 C-atoms, benzyl or a carbamoyl residue -CO-NH-R<SP>15</SP> wherein R<SP>15</SP> is alkyl having 1-12 C-atoms, cyclohexyl, aralkyl having 7 or 8 C-atoms or aryl having 6-12 C-atoms, and if n is 2 Y is one of the groups wherein R<SP>16</SP> is a divalent acyl residue derived from an aliphatic; aromatic or araliphatic dicarboxylic acid having up to 12 C-atoms or R<SP>16</SP> is a dicarbamoyl residue -CONH-R<SP>17</SP>- NHCO-, wherein R<SP>17</SP> is alkylene having 2 to 8 C-atoms, arylene having 6 to 12 C-atoms, xylylene or methane diphenylene. The compounds of Formula I can be prepared from the corresponding 4 oxo piperidines by reaction with polyols Y(OH) 2n with acidic catalysts. |
| priorityDate | 1975-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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