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filingDate 1975-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1977-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1475271-A
titleOfInvention 1-aryl-2-1-imidazolyl-alkyl ethers and thioethers and their use as antifungal agents
abstract 1475271 1 - Aryl - 2 - (1 - imidazolyl)alkyl ethers and thioethers PFIZER Ltd 28 April 1976 [30 April 1975] 17922/75 Heading C2C Novel 1 - aryl - 2 - (1 - imidazolyl)alkyl ethers and thioethers having the general formula wherein R<SP>1</SP>, R<SP>2</SP>, R<SP>3</SP> and R<SP>4</SP> are hydrogen or (C 1 -C 6 )alkyl; Ar is phenyl optionally substituted by one or more halogen (C 1 -C 6 )alkyl or (C 1 -C 6 )alkoxy groups, or a trienyl or halothienyl group; Z is oxygen or sulphur; n is 1 or 2; and Y is an aromatic heterocyclic radical optionally substituted with one or more halogen, alkyl or alkoxy groups, and pharmaceutically acceptable acid addition salts thereof are prepared by reacting an alkali metal salt of a compound of the formula with a compound of the formula wherein X is halogen. The novel compounds are useful in treating fungal infections.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5112985-A
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Total number of triples: 28.