http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1473733-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d629f98a51b15993f56f9e04fdea237f |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-234 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-234 |
filingDate | 1974-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1977-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1473733-A |
titleOfInvention | Pseudotrisaccharides and methods for their production |
abstract | 1473733 Pseudo trisaccharides SCHERICO Ltd 1 Aug 1974 [6 Aug 1973 19 March 1974 (2)] 33968/74 Heading C2C The invention comprises 1-N substituted derivatives of the 4,5-di-(aminoglycosyl)-1,3- diaminocyclitols gentamicin A, gentamicin B, gentamicin B 1 , gentamicin C 1 , gentamicin C 1a , gentamicin C 2 , gentamicin C 2a , gentamicin C 2b , gentamicin X 2 , sisomicin, vendamicin, tobramycin, Antibiotic G-418, Antibiotic 66-40B, Antibiotic 66-40D, Antibiotic J1-20A, Antibiotic J1-20B, Antibiotic G-52, mutamicin 1, mutamicin 2, mutamicin 4, mutamicin 5 and mutamicin 6, where the substituent is -CH 2 X with X being hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, hydroxyalkyl, aminoalkyl, N-alkylaminoalkyl, aminohydroxyalkyl, N-alkylaminohydroxyalkyl, phenyl, benzyl or tolyl, said aliphatic radicals having up to seven carbon atoms and, if substituted by amino and hydroxy, bearing the substituents on different C atoms and pharmaceutically acceptable acid addition salts thereof. The compounds of the invention may be prepared by treating one of the above named 4,6-di-(aminoglycosyl)-1,3- diaminocyclitols which may have aminoprotecting groups at any position other than position 1, with an aldehyde of formula X<SP>1</SP>-CHO, with X<SP>1</SP> being a group as defined for X above wherein any amino or hydroxy group present may be protected in the presence of a hydride donor and reducing agent and, if required, removing all protecting groups present in the molecule the last process step being followed by isolating the derivative as such or as a pharmaceutically acceptable acid addition salt. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8822424-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8524675-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9266919-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8524689-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8492354-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2293383-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101575311-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8653042-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9688711-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11117915-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE47741-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8658606-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8383596-B2 |
priorityDate | 1973-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.