http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1473119-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-685 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-665 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 |
| filingDate | 1974-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1977-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1473119-A |
| abstract | 1473119 Glycero-phosphoric acid derivatives MAX-PLANCK GES ZUR FORDERUNG DER WISSENSCHAFTEN eV 2 Sept 1974 [6 Sept 1973] 38217/74 Headings C2P and C2C The invention comprises compounds of the general Formula (I) wherein R 1 and R 2 are C 9 to C 17 alkyl and R 3 , R 4 and R 5 are H or CH 3 , and acid addition salts thereof. They are prepared by (a) reacting glycerol with a ketone R 1 C(O)R 2 to form (b) reacting the latter with bromoethyl phosphoric acid dichloride and hydrolysing the product to form and (c) reacting the latter with an aminating agent: (R<SP>3</SP>)(R<SP>4</SP>)NR<SP>5</SP>. Salts may be obtained by mixing stoichiometrically equivalent amounts of the compound (I) and an acid, e.g. HCl, H 2 SO 4 , chloroacetic acid or p-toluene sulphonic acid, in chloroform or other solvent and evaporating to dryness. Step (a) is suitably carried out in an organic solvent (preferably a polar solvent) and in the presence of an acid, e.g. p-toluene sulphonic acid as catalyst and steps (b) and (c) may also be carried out in a polar organic solvent. Water may also be present in step (c). The compounds and their acid addition salts are useful as biodegradable surfactants in detergents and as emulsifiers for foods, e.g. margarine. A glycerol derivative of Formula II in which R 1 and R 2 are each pentadecyl is obtained in Example 1(a) by reacting glycerol with dipentadecyl ketone in benzene in the presence of p-toluene sulphonic acid as catalyst. |
| priorityDate | 1973-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.