http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1472574-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e8017b96287e61d78c8917f25768f846 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4833 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99 |
| filingDate | 1974-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1977-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1472574-A |
| titleOfInvention | Process for the extraction of components having anticoagulant activity -in vivo- from snake venoms and related products |
| abstract | 1472574 Isolating snake venom enzyme LABORATORI BIOCHIMICI FARGALPHARMASINT SpA 5 June 1974 [3 Sept 1973] 24920/74 Heading C3H [Also in Division A5] A process for extracting from snake venom, e.g. from Ancistrodon rhodostoma the enzyme component having in vitro coagulant activity and in vivo anti-coagulant activity comprises chromatographing the venom on a column comprising a support, insoluble in aqueous solutions and having bound thereto a substrate or inhibitor for the enzyme by eluting first with an aqueous buffer solution of pH 6-7 and a molarity of 0À05% until more than 95% of the protein components and in vitro coagulant fractions, different from the desired enzyme has been obtained and secondly with a buffer of pH greater than 9 and a molarity greater than or equal to 0À3 M until the enzyme with in vivo anti-coagulant activity together with less than 5% of protein components is obtained. |
| priorityDate | 1973-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID453034310 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID516892 |
Total number of triples: 18.