http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1463520-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d269c8e41f178194d858c230c9f85e3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-44 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- |
| filingDate | 1974-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1977-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1463520-A |
| titleOfInvention | Process for the production of imidazolines |
| abstract | 1463520 Imidazoline compounds PFIZER Ltd 5 Sept 1975 [6 Sept 1974] 39143/74 Heading C2C The invention comprises a process for preparing compounds of the formula where Q represents a group of the formula in which the free valence may be in any one of the 5-, 6-, 7- or 8-positions in the quinoxaline or quinazoline nucleus; (R<SP>1</SP>) x represents up to 3 optional substituents in any of the remaining 5-, 6-, 7- or 8-positions, each R<SP>1</SP> being a halogen atom or a C 1 -C 6 alkyl, C 1 -C 6 alkoxy or trifluoromethyl group and x being 0 to 3; and R<SP>2</SP> represents an optional substituent in either of the 2- or 3-, or 2- or 4-positions of the quinoxaline or quinazoline nucleus, respectively, R<SP>2</SP> being a hydrogen atom or a C 1 -C 6 alkyl or C 1 -C 6 alkoxy group; which comprises heating a thioureido compound of the formula wherein Q is as defined above, to produce the corresponding isothiocyanate of the formula reacting the isothiocyanate with ethylene diamine to form a #-aminoethyl thioureido compound of the formula cyclizing the #-aminoethyl-thioureido compound to form the compound of the Formula (I), recovering the latter as the product, and, optionally, converting the product into a pharmaceutically acceptable acid addition salt. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5714486-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5552403-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5703077-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7265117-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5773440-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5756503-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5587376-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6323204-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5561132-A |
| priorityDate | 1974-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.