http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1462676-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acae202b6a15394281949545e70d2f6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-44 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-46 |
filingDate | 1974-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1977-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1462676-A |
titleOfInvention | Substituted esters of n-4-quinolyl-anthranilic acids |
abstract | 1462676 Substituted esters of N-(4-quinolyl) anthranilic acid ROUSSEL UCLAF 13 June 1974 [13 June 1973] 26294/74 Heading C2 Novel compounds of the Formula I wherein X, which is attached to the 7- or 8- position of the quinoline ring, is trihalomethyl or trihalomethylthio, Z is -(CH 2 ) n - or wherein n is 2-6 and m and p are 2 or 3, Y 1 and Y 2 , which may be the same or different, are C 1-6 alkyl or Y 1 and Y 2 together are a C 4 or C 5 alkylene radical, and non-toxic acid addition salts thereof may be prepared by esterification of a functional derivative of an acid of the Formula II with an alcohol HO-Z-NY 1 Y 2 , optionally followed by salt formation. N - (8 - trifluoromethyl - 4 - quinolyl)anthranilic acid chloride is prepared by reacting the free acid with thionyl chloride. Pharmaceutical compositions of the compounds of the Formula I or salts thereof with the usual excipients show analgesic and anti-inflammatory activity when administered parenterally, buccally, rectally or topically. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0094065-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0094065-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4767767-A |
priorityDate | 1973-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.