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filingDate 1974-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1976-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1457186-A
titleOfInvention Isoquinoline derivatives and process for their manufacture
abstract 1457186 Therapeutic compositions HOECHST AG 22 Feb 1974 [24 Feb 1973] 8171/74 Heading A5B [Also in Division C2] Therapeutic compositions having hypolipaemic and (in some cases) hypoglycaemic activity and which are preferably administered orally, comprise (with certain exclusions: see Division C2) compounds of formula wherein X is O or S; R<SP>1</SP> is H, C 1-6 alkyl or Ph; R<SP>2</SP> is H, or R<SP>1</SP>-R<SP>2</SP> forms with the ring 4-C atom a carbocyclic 5- or 6-membered ring; R<SP>3</SP>, R<SP>4</SP>, R<SP>5</SP> are each H, halogen or NO 2 ; and R<SP>6</SP>, R<SP>7</SP> are each H or C 1-4 alkoxy. Other pharmaceutically active substances which may be present are antidiabetics such as glycodiazin, tolbutamide, glibenclamide, phenformin, buformin and metformin; circulatory agents such as chromonar and prenylamine; hypotensives such as reserpin, alpha-methyldopa and clonidines; other hypolipaemics; geriatric agents; psycho-pharmaceuticals such as chlordiazepoxide, diazepan or meprobamate; and vitamins.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111039867-A
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