http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1456943-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56666880a5e2b7703e98a4f9b2d9daf6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D271-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D457-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-08 |
| filingDate | 1975-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1456943-A |
| titleOfInvention | 1,1-diaryl-1-oxadiazol-alkylamines a |
| abstract | 1456943 Oxadiazole derivatives G D SEARLE & CO 1 April 1975 [1 April 1974] 13186/75 Heading C2C Novel compounds I in which Alk is C 2-4 alkylene, R is C 1-7 alkyl, Ar is phenyl or pyridyl, X and X<SP>1</SP> are H or halogen and Z is OH, COOH, C 1-7 alkoxy-carbonyl or C 2-8 alkanoyloxy, and acid addition salts thereof, are prepared by (a) dehydrating a compound IV or (b) reacting a tetrazole of Formula II with a compound of formula where R<SP>111</SP> is C 1-7 alkyl, and, if required, when Z in the resulting product is alkanoyloxy, hydrolysing the product to form the corresponding compound in which Z is OH. A resulting compound I in which Z is alkoxycarbonyl may be hydrolysed to a corresponding compound in which Z is COOH. 5 - [1,1 - Diphenyl - 3 - (4 - hydroxy - 4- phenylpiperidino)propyl]-1H-tetrazole is prepared by reacting 2,2-diphenyl-4-bromobutyronitrile with 4-hydroxy-4-phenylpiperidine and treating the resulting 2,2-diphenyl-4-(4-hydroxy-4- phenylpiperidino)butyronitrile with sodium azide. Pharmaceutical compositions having antidiarrheal and analgesic activity comprise a compound I together with a carrier. |
| priorityDate | 1974-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.