http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1444154-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da54f7ebbd2d9d8a82f92aca4d1b4e48 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J53-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J53-007 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 |
| filingDate | 1973-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1444154-A |
| titleOfInvention | 15alpha, 16alpha-delta4-pregnenes |
| abstract | 1444154 15,16 - Methylene - pregn - 4 - enes SCHERING AG 13 Aug 1973 [21 Sept 1972] 38249/73 Heading C2U [Also in Division A5] Novel steroids of the formula wherein R<SP>1</SP> is C 1-5 alkyl and R<SP>2</SP> is organic or inorganic acyl are prepared by acylation of the corresponding 17α-ols, which are also novel and which are prepared as illustrated below for two specific compounds of this class. 17 - Hydroxy - 18 - methyl - 15α,16α - methylene - 19 - nor - #<SP>4</SP> - pregnene - 3,20 - dione is prepared from 18 - methyl - 19 - nor - #<SP>4,16-</SP> pregnadiene - 3,20 - dione via 3,3 - (2<SP>1</SP>,2<SP>1</SP>- dimethyl - 1<SP>1</SP>,3<SP>1</SP> - propylenedioxy) - 18 - methyl- 19 - nor - #<SP>5</SP>,<SP>16</SP> or #<SP>5(10)</SP>,<SP>16</SP> - pregnadien - 20 - one-, the corresponding 17 - hydroxy - #<SP>15</SP> - compound 17,20 # - dihydroxy - 3,3 - (2<SP>1</SP>,2<SP>1</SP> - dimethyl - 1<SP>1</SP>,3<SP>1</SP> propylenedioxy)- 18 - methyl - 19 - nor - #<SP>5</SP>,<SP>15</SP> or #<SP>5(10)</SP>,<SP>15</SP>- pregnadiene, the corresponding 15,16- saturated - 15α,16α - methylene compound and 17 - hydroxy - 3,3 - (2<SP>1</SP>,2<SP>1</SP> - dimethyl - 1<SP>1</SP>,3<SP>1</SP>- propylenedioxy) - 18 - methyl - 15α,16α - methylene - 19 - nor - #<SP>5</SP> or #<SP>5(10)</SP>- pregnan - 20 - one. 17 - Hydroxy - 15α,16α - methylene - 19 - nor- #<SP>4</SP> - pregnene - 3,20 - dione is prepared similarly via the corresponding intermediates. The novel 17-acyloxy steroids possess gestagenic and fertilization-preventing activity and may be made up into pharmaceutical and contraceptive preparations with suitable carriers (see Division A5). |
| priorityDate | 1972-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.