http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1443738-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b460b6e95e64228f98a7ffc6bde16de |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 |
| filingDate | 1973-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1443738-A |
| titleOfInvention | Chemical intermediates |
| abstract | 1443738 Penicillin and cephalosporin salts ASTRA LAKEMEDEL AB 10 Sept 1973 [19 Feb 1973] 42391/73 Heading C2C The invention relates to a quaternary ammonium salt of 6-aminopenicillanic acid, 7- aminocephalosporanic acid, a penicillin or a cephalosporin wherein the ammonium ion has the general formula in which R<SP>1</SP> is a straight or branched alkyl group containing 3 to 6 carbon atoms, a substituted or unsubstituted aryl group or a substituted or unsubstituted aralkyl group and wherein R<SP>2</SP>, R<SP>3</SP> and R<SP>4</SP>, which are the same or different, each is straight or branched alkyl group of 1 to 6 carbon atoms, provided that R<SP>2</SP>, R<SP>3</SP> and R<SP>4</SP> are each an alkyl group with 3-6 carbon atoms when R<SP>1</SP> is an alkyl group. The ammonium ion is preferably the tetra-n-butyl ammonium ion. The ammonium salts of the invention have antibacterial properties and may be administered in a suitable dosage form with an appropriate pharmaceutically acceptable carrier. The ammonium salts may be reacted with an appropriate ester-forming derivative to esterify the carboxy group and thus prepare the ester of a 6-amino penicillanic acid, 7- amino, cephalosporanic acid, a penicillin or a cephalosporin. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4619785-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4820857-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4606865-A |
| priorityDate | 1973-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.