http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1442118-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f9afcd0369d6402247555a4656c0917 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L67-00 |
| filingDate | 1975-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1442118-A |
| titleOfInvention | Piperidine derivatives |
| abstract | 1442118 Diphenylmethylene-diphenylmethyl- and diphenylmethylol-piperidines RICHARDSON-MERRELL Inc 7 Feb 1975 [4 March 1974] 5380/75 Heading C2C The invention comprises compounds of formula and their pharmaceutically acceptable acid addition salts, wherein n is 4 or 5; either R is H or OH, and R<SP>1</SP> is H, or R-R<SP>1</SP> forms a further bond; Y is >CO, >C : HOH or > CHOH; and Z is Ph which may be substituted, possible substituents being given in the Specification. In examples, the ketones are prepared generally by reacting Z-Y-(CH 2 ) n -Cl with the appropriate piperidine compound, and may be either reduced to the alcohols are reacted with NH 2 OH to form the oximes. Alternatively, one substituent or Z may be converted into another. Therapeutic compositions having antihistaminic, antiallergic and bronchodilating activity comprise compounds of the above formula, and may be administered orally, parenterally, intranasally or by spray. |
| priorityDate | 1974-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID154402044 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID432534527 |
Total number of triples: 17.