http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1434147-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0821 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-097 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 |
filingDate | 1974-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1976-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1434147-A |
titleOfInvention | Tripeptides |
abstract | 1434147 Tripeptides TAKEDA YAKUHIN KOGYO KK 12 Feb 1974 [23 Feb 1973] 06238/74 Heading C3H [Also in Division C2] Novel tripeptides of the formula where R 1 , R 2 , R 3 are hydrogen or an alkyl group of 1-3 carbon atoms and X is oxygen or sulphur, or a pharmaceutically acceptable acid salt thereof, are claimed. The compounds are prepared and isolated by a wide variety of conventional methods. The examples describe the preparation of L - 2 - oxo - oxazolidine - 4 - carbonyl - L- histidyl - L - prolineamide; L - trans - 5- methyl - 2 - oxo - oxazolidine - 4 - carbonyl - L- histidyl - L - prolineamide; L - 2 - oxothiazolidine - 4 - carbonyl - L - histidyl - L - prolineamide. The dipeptide, L-histidyl-L-prolineamide dihydrochloride is isolated. The tripeptides exhibit thyrotropin-releasing hormone action and are compounded with conventional pharmaceutically-inactive carriers and diluents to form tablets, capsules, granules or injectable solutions. |
priorityDate | 1973-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.