http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1429096-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb75b0b19820e3833ebdcb31603b242b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-834 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07G11-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-085 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07G11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
| filingDate | 1974-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1429096-A |
| titleOfInvention | Antibiotic 60-6 and a process for the production thereof |
| abstract | 1429096 Antibiotic 60-6 SHIONOGI & CO Ltd 24 April 1974 [25 April 1973] 17941/74 Heading C2A An antibiotic, designated 60-6, which antibiotic is a colourless amphoteric powder which shows no definite M.Pt. but progressively decomposes over 140 C.; which contains C, H, N and O in the following proportions by wt.: which has an optical rotation of [α]<SP>23À0</SP> D + 19À8 3À5 (C=0À172% in dimethylformamide); which has a M.Wt. of 1600 and a neutralization equivalent of 1517; which forms aspartic acid, threonine, serine, valine, alloisoleucine, tryptophan, γ-hydroxylysine, ammonia and a variety of fatty acids of 12-16 carbon atoms upon acid hydrolysis; which has ultraviolet absorption bands (in methanol) at 275, 282 and 290À5 mÁ; which has a solubility as defined; which exhibits positive ninhydrin and Dragendorff colour reactions; which exhibits behaviour on t.l.c. as specified; and which has an infra-red absorption spectrum as shown in the accompanying drawing. The antibiotic may be prepared by cultivating a suitable strain of Bacillus cereus in an aqueous nutrient medium under aerobic conditions. A suitable strain is Bacillus cereus No. 60-6, ATCC No. 21929. Preferred cultivation conditions are a temperature of 20-37 C., submerged aerobic conditions, a nutrient medium pH of 7-8, and the optional presence of a buffering agent and an anti-foaming agent. The cultivation proceeds preferably for 20-100 hours, after which the antibiotic may be isolated by filtering the broth and extracting both cells and filtrate with a suitable solvent. There may be prepared, from the antibiotic, salts such as an acid addition salt, an ammonium salt or a pharmaceutically acceptable salt. The antibiotic may be formed into a pharmaceutical or disinfectant composition by admixture with a suitable diluent, carrier or excipient. |
| priorityDate | 1973-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.