http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1422919-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c999fee6428152a996011d506925c2d7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-803 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-04 |
| filingDate | 1974-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1422919-A |
| titleOfInvention | Selective deacylation of n-acyl dl amino acids and cyclic lactams thereof |
| abstract | 1422919 Selective deacylation of N-acyl-DL- amino acids AJINOMOTO CO Inc 24 April 1974 [24 April 1973] 18023/74 Heading C2C An optically active amino acid is produced from an N-acyl derivative of a racemic amino acid, by causing or allowing an acylase in an aqueous medium having a pH of less than 7 to deacylate selectively the N-acyl derivative of the racemic amino acid so as to form one enantiomorph of the amino acid, the N-acyl derivative of the other enantiomorph of the amino acid, and a carboxylic acid corresponding to the acyl radical; and, at least throughout the selective deacylation, maintaining the aqueous medium in contact with an organic solvent which is immiscible or substantially immiscible with the aqueous medium, the respective equilibrium concentrations of the N-acyl derivative of the racemic amino acid, and of the carboxylic acid in the organic solvent being at least equal to the corresponding concentrations in the aqueous medium. In a modification, the N- acyl derivative of the racemic amino acid is replaced by an N-acyl derivative of a cyclic lactam thereof and the product is an optically active cyclic lactam. The organic solvent is preferably an aliphatic triphosphate, an aliphatic ester, an aliphatic ketone or an alcohol. After the reaction the optically active amino is recovered from the aqueous phase and the organic solvent after being stripped to remove the carboxylic acid may be heated to racemize the N-acyl derivative of the amino acid therein and the resulting solution subjected to the process of the invention. |
| priorityDate | 1973-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.