http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1422304-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K20-195 |
filingDate | 1974-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1976-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1422304-A |
titleOfInvention | Penicillins processes for their preparation and their use as medicaments |
abstract | 1422304 Penicillin derivatives BAYER AG 18 April 1974 [19 April 1973 8 Sept 1973] 17020/74 Heading C2C Novel compounds I (in which R 1 is H, 1-5C alkyl, up to 8C aralkyl, aryl, substituted aryl or thienyl; A is a group of general formula (in which R 2 -R 7 are as R 1 and may be the same or different); B is a group of formula (in which R 8 -R 10 are H, F, Cl, Br, I, 1-6C alkyl, alkoxy, alkylthio or alkylsulphonyl, NO 2 , sulphamyl, CN, di(1-6C alkyl)amino, 1-6C alkanoylamino, 1-6C alkanoyloxy, 1-6C alkylsulphonamido, CF 3 or OH) ; E is O or S; and C* is a carbon atom constituting a centre of chirality) are prepared by reaction of a compound II (in which R 11 -R 13 are all H or R 11 -R 12 is -C(R 14 ) 2 - and R 13 is H or R 11 -R 12 are H and R 13 is trialkylsilyl or R 11 and R 13 are trialkylsilyl and R 12 is H and R 14 is 1-6C alkyl) with a compound III (in which W is halo, azido or a group of formula Compounds III may be prepared by reaction of compounds IV with a compound W-CE-W. Compounds IV may be prepared by reaction of hydrazine with an appropriately substituted acetic acid ester. Pharmaceutical compositions comprise a compound I together with suitable diluents or carriers and are useful as antibiotics and growthpromoters. |
priorityDate | 1973-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.