http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1421488-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97f8939cf76e68731c5704c708ac7a89 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-087 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-082 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
| filingDate | 1973-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1421488-A |
| titleOfInvention | Process for preparing carrier-bonded polypeptides |
| abstract | 1421488 Making carrier-bonded polypeptides by irradiation; modified acrylamide copolymers ROHM GmbH 21 Dec 1973 [23 Dec 1972] 59522/73 Headings C3H and C3P A process for the preparation of carrierbonded polypeptides, for example an enzyme, antibody, hormone or enzyme inhibitor comprises irradiating in an essentially oxygen-free atmosphere an aqueous solution of a polypeptide containing a non-peptidic macromolecular reactive carrier, the said solution being irradiated with UV or visible light in the presence of an organic peroxide. The carrier may be a water soluble, water-swellable or water insoluble macromolecular compound preferably containing carboxylic amide, ester, lactone stemiacetal and/or cyclic ether groups and may be a polysaccharide, e.g. a dextran gel, agarose gel or cellulose, vinyl pyrrolidone or may comprise units of methacrylamide, acrylic or methacrylic acid or water-soluble salts thereof, a hydroxyalkyl ester of acrylic or methacrylic acid, 1,2 or 1,4-butanediol acrylate, or methacrylate, an aminoalkyl ester or aminoalkyl amide of acrylic or methacrylic acid or a quaternization product thereof, or units of divinyl benzene, glycol diacrylate or dimethacrylate, triallyl cyanurate, and may comprise side alkenyl and/or alkylphenyl groups. The irradiation may be performed in the presence, as sensitizer, of propiophenone, xanthene, acetophenone, triacetylbenzene, isobutyrophenone, diphenylpropanone benzaldehyde, triphenylmethyl ketone, carbazole, diphenylene oxide, triphenylamine, dibenzothiophene, o-dibenzoylbenzene, benzophenone, dichlorobenzophenone, diacetylbenzene or flucrene. In Example 8, an acrylamide/2-hydroxyethyl methacrylate copolymer is modified by reaction with p-toluene sulphonyl chloride. In Example 9, a similar copolymer is modified by reaction with 4-methylphenylacetic acid chloride. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-398898-B |
| priorityDate | 1972-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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