http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1414047-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e08a4083bbee3454fd85e27fd5dbf92a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-52 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-205 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-757 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-40 |
| filingDate | 1973-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1975-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1414047-A |
| titleOfInvention | Ursolic acid derivatives |
| abstract | 1414047 Ursolic acid derivatives BIOREX LABORATORIES Ltd 11 March 1974 [15 March 1973] 12427/73 Heading C2U The invention comprises compounds of formula wherein either (i) R<SP>1</SP> is an acyl radical of a polycarboxylic acid, and R<SP>11</SP> is OH (compounds Ia), or (ii) R<SP>1</SP> is H or an acyl radical of a mono- or polycarboxylic acid and R<SP>11</SP> is NR<SP>2</SP>R<SP>3</SP> where R<SP>2</SP> and R<SP>3</SP> are each H, an aliphatic radical of at least 3 carbon atoms or a cycloaliphatic or aromatic radical, or NR<SP>2</SP>R<SP>3</SP> is a heterocyclic radical optionally with further hetero atoms and/or substituents (compounds Ib); and the non- toxic salts of those compounds having at least one free carboxy group and/or at least one basic nitrogen atom. Compounds Ia are prepared by esterification of ursolic acid, and compounds Ib by reaction of an ursolic acid halide or 3-acylate thereof with R<SP>2</SP>R<SP>3</SP>NH. The inventive compounds are interconvertible by salification, desalification, and hydrolysis of 3-acyloxy. An acid chloride is prepared from ursolic acid acetate by the action of thionyl chloride. Oral and parenteral antiinflammatory compositions comprise a compound of the invention and a carrier. |
| priorityDate | 1973-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.